Two sample MR report
CD55_Monocyte (Mono) against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | 0.0999042 | 0.1782520 | 0.6315690 |
| Weighted median | 4 | 0.0540351 | 0.0159395 | 0.0006989 |
| Inverse variance weighted | 4 | 0.0526830 | 0.0141530 | 0.0001973 |
| Simple mode | 4 | 0.0547865 | 0.0223809 | 0.0918497 |
| Weighted mode | 4 | 0.0546504 | 0.0209289 | 0.0795998 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1066825 | 2 | 0.9480564 |
| Inverse variance weighted | 0.1773064 | 3 | 0.9811669 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0205 | 0.0771396 | 0.8153177 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001703 | 0 | TRUE | 0.2168476 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
